Neuroendocrine Tumors: 177Lu-edotreotide vs. Everolimus

We are studying whether a new treatment, 177Lu-edotreotide, can help patients with neuroendocrine tumors of the lung and thymus live longer without disease progression compared to everolimus.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Afinitor
Afinitor is a cancer medicine used to treat certain types of tumors and abnormal growths, including some kidney, breast, and brain tumors.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Edotreotide
Edotreotide is a substance that targets certain neuroendocrine tumors by binding somatostatin receptors to help detect and treat them.
Everolimus
Everolimus is a substance that suppresses the immune system to prevent organ rejection and helps slow growth of certain cancers.
L-Arginine Hydrochloride
L-Arginine hydrochloride is a salt form of the amino acid L-arginine used to support blood vessel health and improve blood flow.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Arginine-Lysine
Lutetium Edotreotide

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aderolio
Aderolio 250 Mcg Tablets
Aderolio 500 Mcg Tablets

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Cliniques Universitaires Saint-Luc
Medical Oncology
Sint-Stevens-Woluwe, Belgium
Centre Hospitalier Universitaire De Liege
Medical Oncology
Tilff, Belgium
Antwerp University Hospital
Medical Oncology
Wilrijk, Belgium

Sponsor: Grupo Espanol De Tumores Neuroendocrinos
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.