Nintedanib for Nosebleeds in Hereditary Hemorrhagic Telangiectasia

We are studying whether nintedanib can help reduce the duration of nosebleeds in patients with hereditary hemorrhagic telangiectasia. The trial also examines its effects on quality of life and potential side effects.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Nintedanib
Nintedanib is a medicine used to slow lung scarring (pulmonary fibrosis) and help people keep breathing better.
Ofev
Ofev is a medicine used to slow down scarring of the lungs in certain progressive lung diseases.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Nintedanib
Nintedanib is a substance that helps slow lung scarring in fibrotic lung diseases and is also used to treat some cancers.
Nintedanib Esylate
Nintedanib esylate is a substance that helps slow lung scarring in progressive fibrotic lung diseases and treats certain cancers.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Agarf
Gevesla
Lunidoc

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hospices Civils De Lyon
Departement of genetics
Bron, France
University Hospital Of Clermont-Ferrand
Internal medecine departement
Clermont-Ferrand, France
Sponsor: Hospices Civils De Lyon
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.