Non-Hodgkin Lymphoma: BMS-986458 Treatment Study

We are testing a new drug, BMS-986458, for people with relapsed or refractory non-Hodgkin lymphoma. The study aims to understand its safety and how it works alone and with other treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Glofitamab
Glofitamab is a lab-made antibody that helps the immune system target and kill abnormal B cells in certain types of B-cell lymphoma.
Mosunetuzumab
Mosunetuzumab is a lab-made antibody that helps the immune system target and kill certain B-cell lymphomas.
Obinutuzumab
Obinutuzumab is a lab-made antibody that targets and helps eliminate B cells to treat certain blood cancers like chronic lymphocytic and follicular lymphoma.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

B-Cell Lymphoma 6 Ligand Directed Degrader
Bms-986458

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut Bergonie
Hematology
Bordeaux, France
Centre Hospitalier Universitaire De Lille
Hôpital Claude Huriez
Loos, France
Hopital Saint Eloi
Hématologie clinique
Montpellier, France

Sponsor: Bristol-Myers Squibb Services Unlimited Company
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.