Non-Small Cell Lung Cancer
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for about 85% of cases. It includes several subtypes and can cause symptoms like persistent cough, chest pain, and difficulty breathing.
Non-Small Cell Lung Cancer: Chemotherapy Plus Osimertinib Study
We are evaluating if adding osimertinib to standard chemotherapy helps patients with advanced non-small cell lung cancer who have progressed after initial osimertinib treatment. This study compares the new treatment approach to chemotherapy with a placebo.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you a male willing to use barrier contraception?
- Do you have non-squamous non-small cell lung cancer (NSCLC)?
- Have you had any treatment for cancer in the last 2 years?
- Are you currently pregnant or breastfeeding?
- Have you had any serious lung problems like pneumonia or lung inflammation that needed steroids?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Osimertinib
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Alimta
Armisarte
Carbo-Cell
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Kliniken der Stadt Koeln gGmbH
2606: Lungenklinik Köln-Merheim
Eil, Germany
Universitaetsklinikum Ulm AöR
2604: Klinik fuer Innere Medizin II Sektion Pneumologie
Klingenstein, Germany
University Hospital Cologne AöR
2605: Klinik I für Innere Medizin
Köln, Germany
Sponsor: AstraZeneca AB
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.