Myxoid and Round Cell Liposarcoma
Myxoid and Round Cell Liposarcoma (MRCLS) are rare types of soft tissue sarcomas that arise from fat cells, characterized by specific cellular patterns and often aggressive behavior.
NY-ESO-1 T-Cells for Synovial Sarcoma and Liposarcoma
We are studying genetically engineered T cells in patients with synovial sarcoma and myxoid/round cell liposarcoma. The goal is to see if this treatment is effective and safe for those with specific tumor markers.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Synovial Sarcoma
Synovial Sarcoma is a rare and aggressive type of soft tissue sarcoma that typically occurs near joints and can affect both adults and children, often presenting as a painful mass.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 10 and 75 years old?
- Do you have advanced (metastatic or unresectable) synovial sarcoma or myxoid/round cell liposarcoma?
- Have you had any treatment for advanced synovial sarcoma or myxoid/round cell liposarcoma before?
- Are you currently pregnant or breastfeeding?
- Do you have any serious heart problems, like congestive heart failure or uncontrolled arrhythmia?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
GSK3377794
Letetresgene Autoleucel
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Centre Hospitalier Universitaire De Bordeaux
Department of Hematology and Cellular Therapy
Canéjan, France
Centre Leon Berard
Cancer Centre of Lyon
Meyzieu, France
Fondazione IRCCS Istituto Nazionale Dei Tumori
Department of Medical Oncology
Milan, Italy
Sponsor: USWM Ct LLC
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.