Obesity
Obesity is a medical condition characterized by excessive body fat that increases the risk of health problems. It is often measured using body mass index (BMI) and can lead to various health issues.
Obesity Treatment: Orforglipron Tablet Study
We are investigating how well a new daily tablet helps people with obesity or overweight, both with and without type 2 diabetes, in reducing weight and improving blood sugar levels compared to a placebo.
1-2 yearsConfirmation phase (III)Partially RemoteInvestigational MedicinesOralEndocrinologyInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Overweight
Overweight refers to having more body weight than is considered healthy, which can lead to obesity and associated health risks. It is typically assessed using BMI.
Type 2 Diabetes
Type 2 Diabetes is a chronic condition that affects the way your body metabolizes sugar (glucose), leading to high blood sugar levels. It is often associated with obesity and can cause various health complications.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 25 and 40 kilograms per square meter in body mass index (BMI)?
- Do you have type 2 diabetes?
- Have you tried to lose weight unsuccessfully at least once before?
- Have you had any major heart problems or heart failure in the last 3 months?
- Are you currently taking any medications or remedies to help with weight loss?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Orforglipron
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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MUDr. Alena Váchová
Diabetologie a obezitologie
České Budějovice, Czechia
Nemocnice Cesky Krumlov a.s.
Interní oddělení
Český Krumlov, Czechia
MaderMED s.r.o.
Interní, diabetologická a cévní ambulance
Ostrava, Czechia
Sponsor: Eli Lilly & Co.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.