Ocular Myasthenia Gravis: Corticosteroids and Rituximab Treatment

We are studying whether immediate corticosteroid therapy combined with rituximab can help prevent worsening symptoms in patients with ocular myasthenia gravis. This trial looks at various health outcomes over two years.

6-12 months ≤5 visits Confirmation phase (III)No Placebo Standard Medicines Oral InjectionNeurologyRheumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cortancyl

Cortancyl is a steroid medicine used to reduce inflammation and treat allergies, asthma, and certain autoimmune or inflammatory conditions.

Imurel

Imurel is a medicine that suppresses the immune system to prevent organ transplant rejection and treat autoimmune diseases like rheumatoid arthritis and Crohn’s.

Paracetamol Panpharma

Paracetamol Panpharma is a medicine that relieves pain and reduces fever.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Azathioprine

Azathioprine is a substance that suppresses the immune system to prevent organ rejection and treat autoimmune diseases.

Dexchlorpheniramine Maleate

Dexchlorpheniramine maleate is a substance that relieves allergy symptoms such as sneezing, runny nose, and itching.

Methylprednisolone

Methylprednisolone is a corticosteroid that reduces inflammation and calms an overactive immune system.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief

6 Years Plus Paracetamol Boots

Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Toulouse

Neurology

Blagnac, France

Centre Hospitalier Universitaire De Bordeaux

Neurology

Bordeaux, France

Hospices Civils De Lyon

Neurology

Bron, France

Sponsor: Hopital Fondation Adolphe De Rothschild

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.