Organ Transplantation: Custodiol-N vs. Custodiol Solution

We are studying a new preservation solution for kidney, liver, and pancreas transplants to see if it works as well as the current standard. This research may help improve outcomes for transplant recipients.

>2 years 6-10 visits Confirmation phase (III)No Placebo Investigational MedicinesEndocrinologyHepatologyInternal MedicineNephrologyOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Custodiol

Custodiol is a solution used to protect and preserve organs and heart tissue during transplant or cardiac surgery.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Alanine

Alanine is an amino acid the body uses to build proteins and support energy production and blood sugar regulation.

Arginine

Arginine is an amino acid that helps the body produce nitric oxide to improve blood flow and support wound healing.

Aspartic Acid

Aspartic acid is an amino acid the body uses to build proteins and help metabolism and nerve signaling.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

4-Dimethoxy-N-Methyl-Benzamide

N-Hydroxy-3

N-Acetylhistidine

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Addex

Aminomel

Aminomix 1 Novum

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University Of Graz

Department of Surgery

Graz, Austria

Medizinische Universitaet Innsbruck

Department of Surgery

Innsbruck, Austria

Ordensklinikum Linz GmbH

Department of Surgery

Linz, Austria

Sponsor: Dr. Franz Koehler Chemie GmbH

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.