Osteogenesis Imperfecta: Losartan Therapy Study

We are investigating the right dose of losartan for older adolescents and adults with Osteogenesis Imperfecta. The study aims to see how it affects bone health and quality of life.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Losartan
Losartan is a medicine used to lower high blood pressure and help protect the kidneys in some people with diabetes.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Hydrochlorothiazide
Hydrochlorothiazide is a substance that helps the body remove excess fluid to lower high blood pressure and reduce swelling.
Losartan
Losartan is a substance that helps lower high blood pressure.
Losartan Potassium
Losartan potassium is a substance that helps lower high blood pressure and can protect the heart and kidneys.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Ancozan
Ancozan Comp
Arbartan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Istituto Ortopedico Rizzoli
Department of Rare Skeletal Disorders
Bologna, Italy
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
Endocrinology Unit
Milan, Italy
Sponsor: Istituto Ortopedico Rizzoli
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.