Osteosarcoma: Mifamurtide with Chemotherapy

We are studying whether adding mifamurtide to standard chemotherapy helps improve outcomes for patients with high-risk osteosarcoma. This trial is for individuals aged 2 to 50 who are newly diagnosed with this aggressive cancer.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Etoposide
Etoposide is a chemotherapy medicine used to treat various types of cancer.
Mepact
Mepact is a medicine used to treat a type of bone cancer called osteosarcoma in children and young adults.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cisplatin
Cisplatin is a substance used in chemotherapy to kill or stop the growth of cancer cells.
Doxorubicin Hydrochloride
Doxorubicin hydrochloride is a chemotherapy substance used to treat various cancers by killing or slowing the growth of cancer cells.
Etoposide
Etoposide is a substance used to treat certain cancers by stopping fast-growing cancer cells from dividing.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Celltop
Ebeposid
Eposin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Regional D'Angers
Oncologie pédiatrique
Angers, France
Institut De Cancerologie De L Ouest
Oncologie Médicale
Avignon, France
CHU Besancon
Hémato-Onco-pédiatrie
Besançon, France

Sponsor: Unicancer
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.