Pain Relief for Kids: Fentanyl vs. Ketamine vs. Morphine

We are studying whether intranasal fentanyl or ketamine is more effective than oral morphine for reducing pain in children with limb injuries. This trial involves children aged 2 to 17 in emergency departments.

>2 yearsEfficacy phase (II)Confirmation phase (III)No PlaceboStandard MedicinesOralInjectionInternal MedicineOtolaryngologyPediatrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ketamine
Ketamine is a medicine used to induce anesthesia for procedures and, in some cases, to help relieve severe depression.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Fentanyl Citrate
Fentanyl citrate is a potent opioid substance used to relieve severe pain, especially during surgery or for cancer-related pain.
Ketamine
Ketamine is a fast-acting anesthetic substance used to induce anesthesia, relieve severe pain, and sometimes help with treatment-resistant depression.
Morphine Sulfate
Morphine sulfate is a substance used to relieve severe pain, especially after injury or during surgery.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Calypsol
Cetamina G.L. Pharma
Cetamina Hikma

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Assistance Publique Hopitaux De Paris
92
Boulogne-Billancourt, France
Assistance Publique Hopitaux De Paris
92
Colombes, France
Centre Hospitalier Universitaire De Lille
59
Épône, France
Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.