Pancreatic Cancer: mFOLFIRINOX with Radiation Therapy

We are studying whether adding high-dose radiation therapy to standard chemotherapy helps patients with borderline resectable pancreatic cancer have better surgical outcomes and survival rates.

3-6 months Efficacy phase (II)No Placebo Investigational Medicines InjectionGastroenterologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Abraxane

Abraxane is a chemotherapy medicine used to treat several types of cancer, including breast, lung, and pancreatic cancer.

Calcium Folinate

Calcium folinate helps protect the body from side effects of some chemotherapy drugs and restores folate (vitamin B9) levels.

Fluorouracil Accord Healthcare

Fluorouracil Accord Healthcare is a chemotherapy medicine used to treat several types of cancer by slowing or stopping cancer cell growth.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Calcium Folinate

Calcium folinate is a form of folate used to treat folate deficiency and reduce harmful effects of some chemotherapy.

Fluorouracil

Fluorouracil is a substance used to treat cancer by stopping the growth of cancer cells.

Folinic Acid

Folinic acid is a substance that helps restore folate levels and protects healthy cells during certain chemotherapy treatments.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Gemcitabine

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

5-Fluorouracil

5-Fluorouracil Ebewe

5-Fluorouracil Sandoz

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Chirec

Gastroenterology

Etterbeek, Belgium

Pole Hospitalier Jolimont

Gastroenterology

Fayt-lez-Manage, Belgium

UZ Brussel

Hepatopancreatobiliary Surgery

Ganshoren, Belgium

Sponsor: Hopital Erasme

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.