Personalized Treatment for High-Risk Breast Cancer: PETREMAC Trial

We are studying how personalized therapies can improve outcomes for patients with high-risk breast cancer. The trial looks at treatment responses and aims to enhance surgical options while ensuring safety.

>2 years Efficacy phase (II)No Placebo Investigational Medicines Oral InjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ibrance

Ibrance is a cancer medicine used with hormone therapy to treat certain types of advanced or spread breast cancer.

Lynparza

Lynparza is a cancer medicine used to treat certain ovarian, breast, pancreatic, and prostate cancers, especially those caused by specific gene changes.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Olaparib

Olaparib is a substance used to treat certain cancers by blocking a DNA-repair protein so cancer cells cannot fix damage and die.

Palbociclib

Palbociclib is a substance that slows growth of certain breast cancer cells by blocking proteins that control cell division in advanced disease.

Pertuzumab

Pertuzumab is a targeted antibody used to treat HER2-positive breast cancer by blocking signals that help tumor cells grow.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Perjeta

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Helse Bergen HF

Dpt of oncology

Bergen, Norway

Helse Forde HF

Dpt of oncology

Førde, Norway

Helse Fonna HF

Dpt of oncology

Haugesund, Norway

Sponsor: Helse Bergen HF

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.