Plaque Psoriasis: JNJ-77242113 Study

We are assessing a new treatment for moderate to severe plaque psoriasis to see if it works better than a placebo and an existing medication. This study aims to understand its effectiveness and safety.

>2 years Confirmation phase (III)Investigational Medicines Oral InjectionDermatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Safinamide 100mg Film-Coated Tablets

Safinamide 100mg tablets are used with other medicines to help reduce movement problems that come and go in people with Parkinson’s disease.

Stelara

Stelara is a medicine used to treat certain immune-related inflammatory conditions, including moderate to severe plaque psoriasis, psoriatic arthritis, and Crohn’s disease.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Safinamide

Safinamide is a substance that helps reduce motor fluctuations and improve movement control in people with Parkinson's disease.

Ustekinumab

Ustekinumab is a substance that calms the immune system to treat inflammatory conditions such as psoriasis and inflammatory bowel disease.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ustekinumab

Jnj-77242113

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Absimky

Absimky Accord

Eksunbi

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Vorarlberger Krankenhaus-Betriebsgesellschaft mbH

Abteilung für Dermatologie und Venerologie

Feldkirch, Austria

Johannes Kepler University Linz

Universitätsklinik für Dermatologie und Venerologie

Linz, Austria

Klinik Hietzing

Dermatologische Abteilung

Perchtoldsdorf, Austria

Sponsor: Janssen Cilag International

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.