Plaque Psoriasis: JNJ-77242113 Treatment Study

We are studying a new medication for people with moderate to severe plaque psoriasis. The goal is to see if it works better than a placebo in reducing symptoms.

>2 yearsConfirmation phase (III)Partially RemoteInvestigational MedicinesOralDermatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Darunavir 400 Mg Filmcoated Tablets
Darunavir 400 mg tablets are used with other HIV medicines to help control HIV infection.
Safinamide 100mg Film-Coated Tablets
Safinamide 100mg tablets are used with other medicines to help reduce movement problems that come and go in people with Parkinson’s disease.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Darunavir
Darunavir is a substance that helps control HIV by blocking a viral enzyme needed for the virus to reproduce.
Deucravacitinib
Deucravacitinib is a substance that blocks a specific immune enzyme to lower inflammation, mainly used for moderate-to-severe plaque psoriasis.
Safinamide
Safinamide is a substance that helps reduce motor fluctuations and improve movement control in people with Parkinson's disease.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Jnj-77242113

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Darunasta
Darunavir "sandoz"
Darunavir 600 Mg Filmcoated Tablets

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hautarztpraxis Dr. Mihaescu
Not Applicable
Augsburg, Germany
Thermalsole und Schwefelbad Bentheim GmbH
Dermatology
Bad Bentheim, Germany
Dr. Niesmann And Dr. Othlinghaus GbR
Not Applicable
Bochum, Germany
Sponsor: Janssen - Cilag International
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.