Pleural Mesothelioma: Volrustomig with Carboplatin and Pemetrexed

We are studying a new treatment combination for patients with unresectable pleural mesothelioma. The goal is to see if it works better than current standard care options.

>2 years >20 visits Confirmation phase (III)Post-Trial Drug Access No Placebo Cost Reimbursement Partially Remote Standard Medicines Oral InjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Carboplatin

Carboplatin is a chemotherapy medicine used to treat various types of cancer.

Mycofit

Pemetrexed

Pemetrexed is a chemotherapy medicine used to treat certain types of lung cancer and mesothelioma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Carboplatin

Carboplatin is a chemotherapy substance used to treat various cancers by damaging cancer cells and slowing tumor growth.

Cisplatin

Cisplatin is a substance used in chemotherapy to kill or stop the growth of cancer cells.

Hydroxyethyl Starch 130/0.4

Hydroxyethyl starch 130/0.4 is a synthetic blood volume expander given through a vein to restore blood volume and support circulation during surgery or bleeding.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens

Addex Natriumklorid

Alimta

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Het Ziekenhuisnetwerk Antwerpen

Respiratory

Berchem, Belgium

Jessa Ziekenhuis

Pneumology

Hasselt, Belgium

Universitair Ziekenhuis Gent

Pneumology

Ledeberg, Belgium

Sponsor: AstraZeneca AB

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.