Pneumococcal Vaccine Response in Lymph Nodes

We are studying how the immune system reacts to the pneumococcal vaccine by analyzing lymph nodes. This research may help us understand the timing and types of immune cells involved in the vaccine response.

Efficacy phase (II)No Placebo Investigational Medicines InjectionAllergologyInfectious Diseases

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Pneumovax 23

Pneumovax 23 is a vaccine that helps protect adults and some children from pneumonia and other serious infections caused by pneumococcal bacteria.

Prevenar 13

Prevenar 13 is a vaccine that helps protect infants, children, and adults from serious infections like pneumonia, meningitis, and ear infections caused by bacteria.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Pneumococcal Polysaccharide Serotype 1

Pneumococcal polysaccharide serotype 1 is a vaccine component that helps the immune system prevent infections caused by pneumococcus serotype 1.

Pneumococcal Polysaccharide Serotype 1 Conjugated To Crm197 Adsorbed On Aluminium Phosphate

Pneumococcal polysaccharide serotype 1 conjugated to CRM197 adsorbed on aluminium phosphate is a vaccine component that helps protect against pneumococcal serotype 1 infections.

Pneumococcal Polysaccharide Serotype 10a

Pneumococcal polysaccharide serotype 10A is a vaccine ingredient that helps the immune system protect against pneumonia-causing bacteria of serotype 10A.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Apexxnar

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Pneumovax

Pneumovax®

Prevenar 20

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...

Leiden University Medical Center

Infectious Diseases

Leiden, Netherlands

Sponsor: Leiden University Medical Center

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.