Posaconazole for Young Children with Fungal Infections

We are studying how well Posaconazole works and its safety in children under 2 years old with invasive fungal infections. This research will help us understand its effects compared to older patients.

3-6 months 6-10 visits Efficacy phase (II)No Placebo Standard Medicines Oral InjectionInfectious DiseasesPediatrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Noxafil

Noxafil is an antifungal medicine used to prevent and treat serious fungal infections, especially in people with weakened immune systems.

Posaconazole

Posaconazole is an antifungal medicine used to treat and prevent serious fungal infections.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Posaconazole

Posaconazole is a substance that treats and helps prevent serious fungal infections, especially in people with weakened immune systems.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Gudivin

Ossmiq

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven

pediatric hematology and oncology

Heverlee, Belgium

Universitair Ziekenhuis Gent

pediatric hematology and oncology

Ledeberg, Belgium

Cliniques Universitaires Saint-Luc

pediatric hematology and oncology

Sint-Stevens-Woluwe, Belgium

Sponsor: Merck Sharp & Dohme LLC

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.