Preventing Abscesses After Appendicitis Surgery: ALPACA Trial

We are studying if a special antibiotic wash during surgery can lower the risk of abscesses in patients with complicated appendicitis. This trial aims to improve recovery and reduce complications after surgery.

>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesGastroenterologyInfectious DiseasesOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Clindamycin
Clindamycin is an antibiotic medicine used to treat various bacterial infections, including skin and respiratory infections.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Clindamycin
Clindamycin is an antibiotic substance used to treat various bacterial infections, including skin and respiratory infections.
Clindamycin Phosphate
Clindamycin phosphate is an antibiotic substance used to treat bacterial infections, including skin infections and acne.
Gentamicin
Gentamicin is an antibiotic used to treat serious bacterial infections, especially those caused by gram-negative bacteria.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aknet Duo
Aperox Gel
Cleocin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Amsterdam UMC Stichting
Surgery
Abcoude, Netherlands
Noordwest Ziekenhuisgroep Stichting
Surgery
Alkmaar, Netherlands
Ziekenhuisgroep Twente Stichting
Surgery
Almelo, Netherlands
Sponsor: Stichting Amsterdam UMC
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.