Venous Thromboembolism
Venous Thromboembolism (VTE) is a condition where blood clots form in the veins, often in the legs (deep vein thrombosis) and can travel to the lungs (pulmonary embolism), causing serious health issues.
Preventing Blood Clots: REGN9933 and REGN7508 Study
We are studying two new medications to see if they can help prevent blood clots in adults with a peripherally inserted central catheter. The trial will also assess how safe these treatments are.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 45 kg and 130 kg in weight?
- Do you have a history of blood clots in the arm where the PICC will be placed?
- Are you currently taking blood thinners or medications that prevent blood clotting?
- Have you ever had serious bleeding problems, like from a head injury or surgery?
- Is your overall health status rated as 2 or better on the ECOG scale (meaning you can do normal activities with some limitations)?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Regn7508
Regn9933
Human IgG4 S228P Monoclonal Antibody Against Factor XI And Activated Factor XI
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Multi-profile Hospital for Active Treatment Heart and Brain EAD
First Department of Vascular Surgery at the Clinic of Vascular Surgery – Vascular Surgery Level III
Pleven, Bulgaria
Multiprofile Hospital for Active Treatment Sveta Sofia
Department of Vascular Surgery
Sofia, Bulgaria
Arensia Clinics S.R.L.
Cardiology
Bucharest, Romania
Sponsor: Regeneron Pharmaceuticals Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.