Preventing Chemotherapy-Induced Nausea in Children: IV NEPA Study

We are studying a new intravenous treatment for children with cancer to see if it can effectively prevent nausea and vomiting during chemotherapy. This trial compares IV NEPA with standard treatments to ensure safety and effectiveness.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ivemend
Ivemend is a medicine given by IV to help prevent nausea and vomiting caused by chemotherapy.
Netenax
Ondansetrone Hikma
Ondansetrone Hikma is a medicine used to prevent and treat nausea and vomiting from cancer treatments, radiation therapy, and surgery.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Fosaprepitant
Fosaprepitant is a substance that helps prevent nausea and vomiting caused by chemotherapy and surgery.
Fosnetupitant
Fosnetupitant is a substance that helps prevent nausea and vomiting caused by chemotherapy.
Netilmicin
Netilmicin is an antibiotic substance used to treat serious bacterial infections, particularly those caused by gram-negative bacteria.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Anetena
Arqueta
Atossa

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Nosokomeio Paidon I Agia Sofia
Pediatric Hematology/ Oncology Unit (POHemU)
Athens, Greece
University General Hospital Of Thessaloniki Ahepa
2nd Department of Pediatrics
Sykiés, Greece
Uniwersytecki Dzieciecy Szpital Kliniczny Im. L. Zamenhofa W Bialymstoku
Department of Pediatrics, Oncology and Hematology
Białystok, Poland

Sponsor: Helsinn Healthcare S.A.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.