Prostate Cancer: 177Lu-PSMA-617 Treatment Study

We are evaluating whether adding 177Lu-PSMA-617 to standard treatment helps men with metastatic hormone-sensitive prostate cancer who are not responding well to current therapies. The goal is to see if this combination improves survival and disease control.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Locametz
Pluvicto
Pluvicto is a radioactive medicine used to target and treat advanced prostate cancer that has spread and no longer responds to hormone therapy.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Abiraterone Acetate
Abiraterone acetate is a substance that lowers the body's male hormones to slow the growth of prostate cancer.
Apalutamide
Apalutamide is a substance that blocks male hormone signals to slow the growth of prostate cancer.
Darolutamide
Darolutamide is a substance that blocks male hormones' effects to help treat prostate cancer.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Illuccix
Isoprotrace

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut De Cancerologie De L Ouest
Oncologie Médicale
Angers, France
Centre Jean Perrin
Medical oncology
Beaumont, France
Institut Bergonie
Service de médecine nucléaire
Bordeaux, France

Sponsor: Unicancer
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.