Prostate Cancer: Darolutamide Addition Study

We are studying whether adding darolutamide to standard treatment helps men with metastatic castration-resistant prostate cancer live longer without cancer progression.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cabazitaxel
Cabazitaxel is a chemotherapy medicine used to treat advanced prostate cancer after other treatments have stopped working.
Cabazitaxel Accord
Cabazitaxel Accord is a chemotherapy medicine used to treat advanced prostate cancer that no longer responds to hormone therapy.
Docetaxel Aurovitas
Docetaxel Aurovitas is a cancer treatment medicine used to slow or stop the growth of various tumors.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cabazitaxel
Cabazitaxel is a chemotherapy substance used to treat advanced prostate cancer by killing rapidly dividing cells.
Darolutamide
Darolutamide is a substance that blocks male hormones' effects to help treat prostate cancer.
Docetaxel
Docetaxel is a chemotherapy substance used to treat various cancers by stopping cancer cells from dividing.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Bay 1841788

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bendadocel
Cabazitaxel "medical Valley"
Cabazitaxel "medical Valley"

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hospital Universitario De Cruces
oncology
Barakaldo, Spain
Hospital Universitario De Navarra
oncology
Barañáin, Spain
Hospital Del Mar
oncology
Barcelona, Spain

Sponsor: Swiss Group for Clinical Cancer Research
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.