Prostate Cancer: Estradiol and Exercise Study

We are exploring whether transdermal estradiol and resistance training can help reduce side effects like sexual dysfunction in men undergoing androgen deprivation therapy for prostate cancer. The study also looks at safety and quality of life improvements.

>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesOralInjectionEndocrinologyUrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Enanton Depot Dual
Estrogel
Estrogel is a hormone medicine applied to the skin to relieve menopausal symptoms like hot flashes and vaginal dryness.
Leuprorelin Sandoz
Leuprorelin Sandoz is a hormone-suppressing medicine used to treat prostate cancer, endometriosis, uterine fibroids, and early puberty.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Estradiol
Estradiol is a hormone used to replace low estrogen and relieve menopausal symptoms.
Estradiol Hemihydrate
Estradiol hemihydrate is a form of the female hormone estrogen used to replace low estrogen and relieve menopausal symptoms.
Leuprorelin
Leuprorelin is a substance that reduces sex hormone production to manage prostate cancer, endometriosis, precocious puberty, and other hormone-related conditions.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Activelle
Activelle Low
Activelle Minor

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Central Finland Hospital District Central Finland Hospital Nova
Urology
Jyväskylä, Finland
University Of Jyvaskyla
The Faculty of Sport and Health Science
Jyväskylä, Finland
Tampere University Hospital
Urology
Tampere, Finland
Sponsor: Central Finland Hospital District Central Finland Hospital Nova
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.