Prostate Cancer: Lutetium-177 vs. Standard Treatments

We are comparing a new treatment called Lutetium-177 with standard medications for men with metastatic hormone-sensitive prostate cancer. The goal is to see which option better delays disease progression and improves survival.

>2 years 6-10 visits Confirmation phase (III)No Placebo Partially Remote Standard Medicines Oral InjectionOncologyUrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

177lu Psma I&t

177Lu PSMA I&T is a targeted radiation treatment used for advanced prostate cancer that has spread.

Erleada

Erleada is a medicine used to treat prostate cancer by helping slow cancer growth and delay disease progression.

Ondansetron

Ondansetron is a medicine that helps prevent nausea and vomiting after surgery or during cancer treatment.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Abiraterone Acetate

Abiraterone acetate is a substance that lowers the body's male hormones to slow the growth of prostate cancer.

Apalutamide

Apalutamide is a substance that blocks male hormone signals to slow the growth of prostate cancer.

Betamethasone

Betamethasone is a corticosteroid substance that reduces inflammation and suppresses immune responses for conditions like eczema, allergies, and arthritis.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Atossa

Avessaron

Cellondan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Region Vaesterbotten

Cancercentrum

Umeå, Sweden

Sponsor: Region Västerbotten

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.