Prostate Cancer: Short vs. Long-Term Androgen Deprivation Therapy

We are comparing short-term and long-term hormone therapy combined with radiotherapy for men with prostate cancer that has returned after surgery. The goal is to see which approach may improve survival and reduce recurrence.

1-2 yearsConfirmation phase (III)No PlaceboStandard MedicinesOralInjectionOncologyUrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Bicalutamid Aristo
Bicalutamid Aristo is a medicine used to treat prostate cancer by blocking male hormones the cancer needs to grow.
Decapeptyl Semestral
Decapeptyl Semestral is a six-month injection that lowers sex hormones to treat hormone-related conditions such as advanced prostate cancer.
Eligard Semestral
Eligard Semestral is a medicine that lowers testosterone to help treat prostate cancer, given as a six-month injection.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bicalutamide
Bicalutamide is a substance that blocks male hormones to slow the growth of prostate cancer.
Goserelin
Goserelin is a substance that lowers sex hormone levels to treat hormone-sensitive cancers and conditions.
Goserelin Acetate
Goserelin acetate is a substance that lowers sex hormone levels to treat hormone-sensitive cancers and certain reproductive conditions like endometriosis or early puberty.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Algonad
Almus
Androbloc

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hospital Universitario De Cruces
Oncología Radioterápica
Barakaldo, Spain
Hospital De La Santa Creu I Sant Pau
Oncología Radioterápica
Barbastro, Spain
Hospital Universitari Vall D Hebron
Oncología Radioterápica
Barcelona, Spain
Sponsor: Instituto De Investigacion En Oncología Radioterapica FEOR
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.