Protecting Children from Radiation-Induced Hypothyroidism

We are studying whether TSH suppression during radiation therapy can lower the risk of hypothyroidism in children with medulloblastoma and lymphomas. This trial also examines any changes in thyroid tissue after treatment.

>2 years Confirmation phase (III)No Placebo Standard Medicines OralEndocrinologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Levotiroxina Teva

Levotiroxina Teva is a medicine used to treat an underactive thyroid by replacing missing thyroid hormone.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Levothyroxine

Levothyroxine is a substance used to replace low thyroid hormones.

Levothyroxine Sodium

Levothyroxine sodium is a substance used to replace low thyroid hormones.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Accu-Thyrox

Althyxin

Dexnón

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Fondazione IRCCS Istituto Nazionale Dei Tumori

Pediatric Oncology

Milan, Italy

Sponsor: Fondazione IRCCS Istituto Nazionale Dei Tumori

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.