Psilocybin for Depression in Cancer Patients

We are studying whether psilocybin can quickly improve depression in people with cancer compared to ketamine and midazolam. The trial will also look at its effects on quality of life and overall well-being.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ketamine Hydrochloride
Ketamine hydrochloride is a substance that produces short-term anesthesia and pain relief for surgeries and severe pain.
Midazolam
Midazolam is a substance that produces sedation and reduces anxiety, often used to calm patients before procedures or help control seizures.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Psilocybine

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Masarykuv Onkologicky Ustav
Klinika komplexní onkologické péče, Centrum paliativní péče
Brno, Czechia
Narodni Ustav Dusevniho Zdravi
Výzkumné centrum NUDZ
Roztoky, Czechia
Sponsor: Narodni Ustav Dusevniho Zdravi
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.