Treatment-Resistant Depression
Treatment-resistant depression (TRD) is a form of major depression that does not improve with standard treatments, such as antidepressant medications or therapy, requiring alternative approaches to manage symptoms.
Psilocybin for Hospitalized Patients with Treatment-Resistant Depression
We are studying the safety and feasibility of psilocybin-assisted psychotherapy for patients with treatment-resistant depression in a hospital setting. This research aims to explore its effects on depression and the overall experience of patients.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years old or older?
- Do you have major depressive disorder (not including any psychotic features)?
- Are you currently pregnant or breastfeeding?
- Are you taking any medications like Lithium, Disulfiram, or MAOIs?
- Have you had a recent stroke or heart attack in the past year?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Psilocybin
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Universitair Ziekenhuis Gent
Medical head of department - Psychiatrie
Ledeberg, Belgium
Sponsor: Universitair Ziekenhuis Gent
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.