Psoriatic Arthritis: Tapering Immunosuppressive Therapy

We are studying whether reducing immunosuppressive medication helps adults with psoriatic arthritis maintain stable disease activity. The trial also looks at the safety of this approach.

>2 years Confirmation phase (III)No Placebo Standard Medicines Oral InjectionInternal MedicineRheumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Apremilast

Apremilast is a pill that helps control symptoms of psoriasis and psoriatic arthritis by reducing inflammation.

Cimzia

Cimzia is a medicine that reduces inflammation to treat autoimmune conditions such as rheumatoid arthritis and Crohn’s disease.

Cosentyx

Cosentyx is a medicine used to treat plaque psoriasis, psoriatic arthritis, and certain inflammatory spine conditions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Abatacept

Abatacept is a substance that reduces immune system overactivity to treat autoimmune conditions such as rheumatoid arthritis.

Adalimumab

Adalimumab is a biologic that blocks a key inflammatory protein (TNF) to reduce inflammation in autoimmune conditions like rheumatoid arthritis and Crohn's disease.

Apremilast

Apremilast is a substance that reduces inflammation to help treat conditions like psoriasis and psoriatic arthritis.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Absimky

Absimky Accord

Adelcort®

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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InnKlinikum Burghausen

MED Bayern OST MVZ Burghausen Altötting

Burghausen, Germany

Universitaetsklinikum Erlangen AöR

Medizinische Klinik 3

Erlangen, Germany

Klinikum Nuernberg

Klinik für Innere Medizin 5

Nürnberg, Germany

Sponsor: Universitaetsklinikum Erlangen AöR

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.