Pulmonary Arterial Hypertension: Treprostinil Sodium for Kids

We are studying the safety and tolerability of a new preservative-free medication for children with pulmonary arterial hypertension. The trial also looks at how it may improve their quality of life and symptoms.

3-6 months ≤5 visits Confirmation phase (III)No Placebo Partially Remote Investigational Medicines InjectionPediatricsPulmonology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Trepulmix

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Trepibutone

Trepibutone is a substance that helps relieve biliary tract spasms and improves bile flow to ease gallbladder-related discomfort.

Treprostinil

Treprostinil is a substance that widens lung blood vessels to lower pulmonary blood pressure and improves breathing and ability to exercise.

Treprostinil Sodium

Treprostinil sodium is a substance that widens lung blood vessels to lower high pressure in the lungs for people with pulmonary arterial hypertension.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Trepaed

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Hoppas

Remodulin

Treposa

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University of Vienna

Universitatsklinik fur Kinder- und Jugendheitkunde Klinische Abteilung fur Padiatrische Kardiologie

Vienna, Austria

Assistance Publique Hopitaux De Paris

Cardiologie Infantile

Montrouge, France

LMU Klinikum Muenchen AöR

Pediatric cardiology and Intensive Care

Neuried, Germany

Sponsor: Aop Orphan Pharmaceuticals GmbH

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.