Quizartinib for Pediatric FLT3-ITD Positive AML

We are studying the safety and effectiveness of quizartinib combined with chemotherapy in children and adolescents newly diagnosed with FLT3-ITD positive acute myeloid leukemia. This trial aims to see if it helps improve treatment outcomes compared to standard therapies.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Quizartinib
Quizartinib is a substance that targets a specific cancer-causing protein to treat certain types of acute myeloid leukemia.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven
Pediatric Hemato-Oncology
Heverlee, Belgium
Association Hospitaliere De Bruxelles Hopital Universitaire Des Enfants Reine Fabiola
Pediatric Hemato-Oncology
Jette, Belgium
Universitair Ziekenhuis Gent
Pediatric Hemato-Oncology
Ledeberg, Belgium

Sponsor: Prinses Maxima Centrum voor Kinderoncologie B.V.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.