Focal Cortical Dysplasia (FCD)
Focal Cortical Dysplasia (FCD) is a rare brain malformation that can lead to seizures and developmental issues. It occurs when the brain's cortex does not develop normally, affecting how the brain functions.
Radiprodil for Seizures in Tuberous Sclerosis and Focal Cortical Dysplasia
We are studying the safety and effects of radiprodil on seizures and behavior in patients with Tuberous Sclerosis Complex or Focal Cortical Dysplasia Type II. This research may help improve treatment options for these conditions.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Tuberous Sclerosis Complex (TSC)
Tuberous Sclerosis Complex (TSC) is a genetic disorder that causes non-cancerous tumors to form in various organs, particularly the brain, skin, and kidneys. It can lead to seizures, developmental delays, and other health issues.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 6 months and 18 years old?
- Have you had at least 8 seizures in the past month?
- Do you have severe liver problems (Child-Pugh grade C)?
- Have you had brain surgery in the last 6 months?
- Are you currently taking any medications like felbamate, memantine, or perampanel?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Radiprodil
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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UZ Leuven
Pediatric neurology
Heverlee, Belgium
Antwerp University Hospital
Pediatric neurology
Wilrijk, Belgium
Azienda Ospedaliera Universitaria Meyer IRCCS
Center of Excellence in Neurosciences
Florence, Italy
Sponsor: Grin Therapeutics Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.