Refractory Solid Tumors: Propranolol and Vinorelbine Study

We are testing a combination of Propranolol and Vinorelbine in children and teenagers with hard-to-treat solid tumors. The study aims to find the safest dose and evaluate how well this treatment works over time.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Hemangiol
Hemangiol is a medicine used to shrink and treat infantile hemangiomas, the common blood-vessel birthmarks that appear in babies.
Navelbine
Navelbine is a chemotherapy medicine used to treat certain cancers, including lung and breast cancer.
Propranolol Teva
Propranolol Teva is a medicine that treats high blood pressure, certain heart rhythm problems, helps prevent migraines, and can reduce anxiety symptoms.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Propranolol Hydrochloride
Propranolol hydrochloride is a beta-blocker that lowers heart rate and blood pressure to treat heart-related conditions and reduce physical anxiety symptoms.
Vinorelbine
Vinorelbine is a substance used to treat certain cancers by preventing cancer cells from dividing.
Vinorelbine Tartrate
Vinorelbine tartrate is a substance used in chemotherapy to treat certain types of cancer, especially lung and breast cancer.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Anaprilīns
Anaprilīns
Angilol

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Bordeaux
Hemato-oncologie pédiatrique
Bordeaux, France
Les Hopitaux Universitaires De Strasbourg
Hématologie Oncologie Pédiatrique
Eckbolsheim, France
Centre Hospitalier Regional De Marseille
Hematologie et Oncologie Pédiatrique
Marseille, France

Sponsor: Centre Hospitalier Regional De Marseille
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.