Relapsing Multiple Sclerosis: Remibrutinib vs. Ocrelizumab

We are studying whether remibrutinib is as effective and safe as ocrelizumab for people with relapsing multiple sclerosis after switching treatments. This trial will help us understand the best options for managing the disease.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ocrevus
Ocrevus is a medicine used to treat multiple sclerosis, helping reduce relapses and slow progression of disability.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ocrelizumab
Ocrelizumab is a substance used to treat multiple sclerosis by targeting specific immune cells to reduce inflammation and nerve damage.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Lou064
Remibrutinib

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Az St-Jan Brugge-Oostende A.V.
#2001: Neurology
Sint-Andries, Belgium
Region Midtjylland
#2011: Neurologisk Forskning
Århus, Denmark
Rigshospitalet
#2012: Afdeling for Hjerne- og Nervesygdomme
Glostrup, Denmark

Sponsor: Novartis Pharma AG
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.