Retinoblastoma: New Conservative Treatment Approaches

We are studying different chemotherapy and local treatment methods for children with retinoblastoma to see if they can preserve vision without using radiation. This trial includes various patient groups based on their specific conditions.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Carboplatine Teva
Carboplatine Teva is a chemotherapy medicine used to treat various types of cancer.
Etoposide Teva
Etoposide Teva is a chemotherapy medicine used to treat several types of cancer.
Melphalan
Melphalan is a chemotherapy medicine used to treat certain cancers, especially multiple myeloma and ovarian cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Carboplatin
Carboplatin is a chemotherapy substance used to treat various cancers by damaging cancer cells and slowing tumor growth.
Etoposide
Etoposide is a substance used to treat certain cancers by stopping fast-growing cancer cells from dividing.
Melphalan
Melphalan is a substance used to treat certain cancers by killing or stopping the growth of cancer cells.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alkeran
Carbo-Cell
Carbomedac

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire D'Angers
Unité d’Hématologie/Oncologie/Immunologie Pédiatrique
Angers, France
Centre Hospitalier Universitaire De Toulouse
Département Médico-Chirurgical de Pédiatrie
Blagnac, France
Centre Hospitalier Universitaire De Bordeaux
Hémato-oncologie pédiatrique Département de Pédiatrie-
Bordeaux, France

Sponsor: Institut Curie
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.