Retinoblastoma: New Treatment Strategies

We are studying the effectiveness of a new chemotherapy method and other conservative treatments for children with retinoblastoma. Our goal is to see how well these treatments control the disease and support visual health.

>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesInjectionOncologyOphthalmology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Carboplatine Hospira
Carboplatine Hospira is a chemotherapy medicine used to treat several types of cancer, including ovarian and lung cancers.
Melphalan Tillomed
Melphalan Tillomed is a chemotherapy medicine used to treat certain cancers, including multiple myeloma and ovarian cancer.
Topotecan
Topotecan is a chemotherapy medicine used to treat certain cancers, including ovarian and small-cell lung cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Carboplatin
Carboplatin is a chemotherapy substance used to treat various cancers by damaging cancer cells and slowing tumor growth.
Etoposide
Etoposide is a substance used to treat certain cancers by stopping fast-growing cancer cells from dividing.
Melphalan
Melphalan is a substance used to treat certain cancers by killing or stopping the growth of cancer cells.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alkeran
Carbo-Cell
Carbomedac

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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CHU Amiens - Groupe Hospitalier Sud
Onco-hématologie pédiatrique
Amiens, France
Centre Hospitalier Universitaire D'Angers
oncologie pediatrie
Angers, France
Centre Hospitalier Universitaire De Toulouse
pediatrie oncologie hematologie
Blagnac, France
Sponsor: Institut Curie
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.