Rheumatoid Arthritis: Spironolactone Study

We are investigating whether spironolactone can help reduce symptoms in people with active rheumatoid arthritis. The study will also monitor safety and other health indicators.

>2 years 6-10 visits Confirmation phase (III)Partially Remote Standard Medicines OralInternal MedicineRheumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Spironolactone Viatris

Spironolactone Viatris is a medicine that helps the body remove excess water and salt, used for fluid buildup and high blood pressure.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Magnesium Stearate

Magnesium stearate is a substance used as a lubricant in tablet and capsule production to prevent ingredients from sticking during manufacturing.

Spironolactone

Spironolactone is a substance that reduces fluid retention and lowers blood pressure by blocking aldosterone, also used for hormone-related acne.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aldactacine

Aldactazide

Aldactazine

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Les Hopitaux Universitaires De Strasbourg

Rheumatology

Strasbourg, France

Medical Center - University Of Freiburg

Innere Medizin

Freiburg, Germany

Universitaetsklinikum Heidelberg AöR

Rheumatology

Heidelberg, Germany

Sponsor: Les Hopitaux Universitaires De Strasbourg

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.