Rituximab for Amyotrophic Lateral Sclerosis (ALS)

We are studying whether adding Rituximab to standard treatment can slow symptom progression in ALS patients. The trial also monitors safety and various health indicators.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Isotonische Kochsalzlösung Fresenius
Isotonische Kochsalzlösung Fresenius is a sterile salt solution used to replace body fluids, hydrate patients, and clean wounds or medical devices.
Methylprednisolon Acis
Methylprednisolon Acis is a steroid medicine used to reduce inflammation and treat allergic reactions, asthma flare-ups, and some immune system disorders.
Paracetamol B. Braun
Paracetamol B. Braun is a medicine used to relieve pain and reduce fever.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dimetindene Maleate
Dimetindene maleate is a substance that blocks histamine to relieve allergic symptoms like itching, hives, runny nose, and watery eyes.
Methylprednisolone
Methylprednisolone is a corticosteroid that reduces inflammation and calms an overactive immune system.
Methylprednisolone Hydrogen Succinate
Methylprednisolone hydrogen succinate is a corticosteroid substance that rapidly reduces inflammation and suppresses overactive immune responses.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief
6 Years Plus Paracetamol Boots
Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Charite Universitatsmedizin Berlin KöR
Klinik für Neurologie
Berlin, Germany
Deutsches Zentrum Fuer Neurodegenerative Erkrankungen e.V.
Clinical Trial Unit
Bonn, Germany
Sponsor: Deutsches Zentrum Fuer Neurodegenerative Erkrankungen e.V.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.