Scoliosis Surgery: Pooled Plasma vs. Crystalloid

We are studying whether pooled human plasma can reduce blood loss during spinal fusion surgery in children with scoliosis compared to a standard fluid. This trial aims to improve fluid management during surgery.

>2 years≤5 visitsEfficacy phase (II)No PlaceboStandard MedicinesInjectionOrthopedics and TraumatologyPediatrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Octaplasma
Octaplasma is pooled human plasma used to replace proteins that help blood clot in people with bleeding or liver-related clotting problems.
Plasma-Lyte® 148 (Ph 7.4)
Plasma-Lyte 148 is an intravenous fluid used to restore body fluids and salts during dehydration, surgery, or medical emergencies.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Human Plasma Protein
Human plasma protein replaces essential blood proteins to treat low protein levels, bleeding disorders, and immune deficiencies.
Magnesium Chloride Hexahydrate
Magnesium chloride hexahydrate is a magnesium supplement used to restore low magnesium levels and support healthy muscle and nerve function.
Potassium Chloride
Potassium chloride is a substance used to restore low potassium levels in the body and support normal heart and muscle function.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Addex
Albumina Humana Csl Behring
Albumine Humaine Csl Behring

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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HUS-Yhtymae
Department of Pediatric Orthopedics and Traumatology
Helsinki, Finland
Turku University Hospital
Anesthesiology and Intensive Care, Lighthouse Hospital
Turku, Finland
Sponsor: HUS-Yhtymae
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.