Seizure Treatment After Cardiac Arrest: TELSTAR-2 Trial

We are studying whether a stepwise anti-seizure treatment helps improve outcomes for comatose patients who have seizures after cardiac arrest. This trial also looks at the healthcare costs associated with this treatment.

Confirmation phase (III)No PlaceboStandard MedicinesInjectionCardiologyInternal MedicineNeurology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Depakine I.V. 400
Depakine I.V. 400 is a medicine given into a vein to help control seizures in people with epilepsy.
Diazepam Cf
Diazepam Cf is a medicine used to treat anxiety, relax muscles, and help control seizures.
Keppra
Keppra is a medicine used to prevent and control seizures in people with epilepsy.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Diazepam
Diazepam is a substance that reduces anxiety, relaxes muscles, and helps control seizures.
Esketamine
Esketamine is a fast-acting antidepressant substance used to relieve depression symptoms when other treatments haven't worked.
Lacosamide
Lacosamide is a substance that helps control seizures in people with epilepsy by calming overactive brain activity.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Absenor
Absenor Depot
Ácido Valproico Altan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Brussel
Intensive care
Ganshoren, Belgium
Centre hospitalier universitaire de Tivoli Institut medical des Mutualites socialistes
Intensive care
Haine-Saint-Pierre, Belgium
CHC MontLegia
Neurology
Liège, Belgium
Sponsor: Universiteit Twente
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.