Semaglutide for Obesity and Resistant Hypertension

We are exploring whether semaglutide can help people with obesity and resistant hypertension better control their blood pressure compared to a placebo. This study aims to assess if this approach is feasible.

6-12 months Confirmation phase (III)Cost Reimbursement Partially Remote Standard Medicines InjectionCardiologyEndocrinologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ozempic

Ozempic is a medicine that helps lower blood sugar in adults with type 2 diabetes.

Wegovy Flextouch

Wegovy Flextouch is a prescription injectable medicine used to help adults lose weight and keep it off when combined with diet and exercise.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Semaglutide

Semaglutide is a substance that helps lower blood sugar in people with type 2 diabetes and can also reduce appetite to aid weight loss.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Rybelsus

Wegovy

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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St James's Hospital

Clinical pharmacology and therapeutics

Crumlin, Ireland

TURLOUGHMORE MEDICAL CENTRE

General Medicine/Practice

Galway, Ireland

University Hospital Galway

Endocrinology/ Pharmacology & Therapeutics

Galway, Ireland

Sponsor: Trinity College Dublin

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.