Septic Shock
Septic shock is a life-threatening condition that occurs when an infection leads to dangerously low blood pressure and organ failure, often requiring immediate medical attention.
Septic Shock: Ivabradine for Heart Rate Control
We are studying whether Ivabradine can help control heart rate and improve survival in patients with septic shock. This trial compares the medication to a placebo to assess its effectiveness.
>2 yearsConfirmation phase (III)Standard MedicinesOralCardiologyInfectious DiseasesInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years of age or older?
- Do you have a proven or suspected site of infection?
- Are you currently experiencing septic shock (low blood pressure that doesn't improve with fluids) for less than 24 hours?
- Are you pregnant or breastfeeding?
- Do you have severe kidney disease (creatinine clearance less than 15 ml/min) or severe liver disease (prothrombin time less than 20%)?
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Apredonav
Arparial
Bivelen
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Assistance Publique Hopitaux De Paris
Réanimation Médicale et toxicologique
Angers, France
Centre Hospitalier Victor Dupouy
Service de Réanimation Polyvalente
Argenteuil, France
Assistance Publique Hopitaux De Paris
Réanimation médico-chirurgicale
Bagnolet, France
Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.