Severe Brain Injury and Disorder of Consciousness
A Disorder of Consciousness occurs when a person is unable to respond to their environment due to severe brain injury, which can result in states like coma or vegetative state.
Severe Brain Injury: Apomorphine Treatment Study
We are investigating whether apomorphine can help patients with disorders of consciousness. The study also aims to identify which patients may respond best to this treatment.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 18 and 70 years old?
- Have you been diagnosed with unresponsive wakefulness syndrome or minimally conscious state?
- Have you taken any medications like amantadine, bromocriptine, or l-dopa in the last 2 weeks?
- Have you had any significant heart problems or a QT interval over 480ms in the last 14 days?
- Do you have any contraindications to MRI, EEG, or PET scans, like electronic devices or active epilepsy?
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Hôpital du Valdor
Medical Direction - Rehabilitation
Bressoux, Belgium
Centre Hospitalier Universitaire De Liege
Anaesthesia and intensive care
Tilff, Belgium
Hospital Nisa Sevilla Aljarafe
Servicio de Neurorrehabilitación Hospitales Vithas
Castilleja de la Cuesta, Spain
Sponsor: Universite De Liege
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.