Severe Community-Acquired Pneumonia: AON-D21 Treatment Study

We are testing a new drug, AON-D21, as an additional treatment for patients with severe community-acquired pneumonia in intensive care. The study aims to assess its safety and effectiveness compared to a placebo.

≤3 months>20 visitsEfficacy phase (II)Cost ReimbursementInvestigational MedicinesInjectionInternal MedicinePulmonology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Glucose 5% Basi
Glucose 5% Basi is a sterile sugar solution given into a vein to provide fluids and quick energy and prevent low blood sugar.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Glucose
Glucose is a simple sugar substance that supplies quick energy and is used to raise low blood sugar levels.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Aon-D21

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Ardeanutrisol G
Dextrose Bradex
Dextrose Demo

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Clinique Saint-Pierre Ottignies (CSPO)
Service des soins intensifs
Ottignies, Belgium
Cliniques Saint Luc
Service de soins intensifs
Sint-Stevens-Woluwe, Belgium
CHU De Liege
Service de soins intensifs
Tilff, Belgium
Sponsor: Aptarion Biotech AG
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.