Severe Hyponatremia: DDAVP Treatment Study

We are investigating whether DDAVP can help prevent sodium overcorrection in patients with severe hyponatremia. This study aims to improve safety and outcomes for those experiencing dangerously low sodium levels.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Chlorure De Potassium B. Braun
Chlorure De Potassium B. Braun is a medical solution used to replace or prevent low potassium levels in the blood.
Chlorure De Sodium Aguettant
Chlorure De Sodium Aguettant is a sterile saline solution used to replace fluids, clean wounds, or dilute medicines during medical care.
Chlorure De Sodium Hypertonique Lavoisier
A concentrated saline solution used to help loosen and clear mucus from the nose or lungs.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Desmopressin
Desmopressin is a substance that reduces urine production and helps control excessive urination and bedwetting by mimicking a natural antidiuretic hormone.
Desmopressin Acetate
Desmopressin acetate is a synthetic hormone that reduces urine production to treat excessive urination and bedwetting.
Desmopressin Acetate Trihydrate
Desmopressin acetate trihydrate is a substance that reduces excess urine production and helps control bedwetting and some bleeding problems.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

1 M Kalijev Klorid Hztm
1 M-Kaliumchlorid-Lösung Deltamedica
1m-Kaliumchlorid-Lösung Fresenius

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Assistance Publique Hopitaux De Paris
Imagerie Médicale
Bondy, France
Assistance Publique Hopitaux De Paris
Réanimation
Bondy, France
Groupe Hospitalier Nord Essonne
Imagerie Médicale
Bures-sur-Yvette, France

Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.