Severe Systemic Sclerosis: Stem Cell Treatment Study

We are investigating the safety of a new stem cell therapy for people with severe systemic sclerosis. The study aims to see if this treatment can improve skin and lung function.

>2 years6-10 visitsEfficacy phase (II)Post-Trial Drug AccessInvestigational MedicinesInjectionInternal MedicineRheumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ex Vivo Expanded Autologous Human Corneal Epithelial Cells Containing Stem Cells
Patient's own corneal cells grown outside the body that contain stem cells are used to restore and repair a damaged corneal surface, improving vision.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Allogeneic Mesenchymal Stromal Cells Derived From Adipose Tissue

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Assistance Publique Hopitaux De Paris
Unité de Médecine Interne (UF 04): CRMR MATHEC, Maladies auto-immunes et thérapie cellulaire
Quinze-Vingts, France
Centre Hospitalier Universitaire De Toulouse
Medecine interne et immunologie Clinique
Ramonville-Saint-Agne, France
Centre Hospitalier Universitaire De Rennes
Médecine interne et immunologie clinique
Rennes, France
Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.