Sickle Cell Disease
Sickle Cell Disease (SCD) is a genetic blood disorder characterized by the production of abnormal hemoglobin, leading to distorted (sickle-shaped) red blood cells that can cause pain, anemia, and various complications.
Sickle Cell Disease: Tebapivat Study
We are investigating a new medication, tebapivat, to see if it helps improve anemia in people with sickle cell disease. The study will also look at its safety and effects on fatigue and pain.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 16 and 75 years old?
- Do you have sickle cell disease (SCD) or any sickle cell syndrome variant?
- Are you currently pregnant or breastfeeding?
- Are you taking any medications for sickle cell disease, like hydroxyurea, and has your dose been stable for at least 90 days?
- Have you had more than 10 sickle cell pain crises in the past year?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
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Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Centre Hospitalier Regional De La Citadelle
Hematology
Liège, Belgium
CHC MontLegia
Hematology
Liège, Belgium
Hopital Erasme
Hematology
Negenmanneke, Belgium
Sponsor: Agios Pharmaceuticals Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.