Sickle Cell Pain Relief: Intranasal Sufentanil Study

We are investigating whether a new nasal spray for pain relief helps children with severe sickle cell pain crises feel better faster than standard treatments. This study aims to improve pain management in pediatric emergency care.

>2 yearsConfirmation phase (III)Investigational MedicinesInjectionHematologyInternal MedicinePediatrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Chlorure De Sodium Lavoisier
Chlorure De Sodium Lavoisier is a sterile saltwater solution used to replace fluids and salts, dilute medicines for injection, or clean wounds.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Morphine Hydrochloride
Morphine hydrochloride is a substance that relieves severe pain by decreasing the body's perception of pain.
Sodium Chloride
Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.
Sodium Chloride Solution 0.9%
Sodium chloride 0.9% is a sterile salt solution used to replace fluids and electrolytes, hydrate patients, and clean wounds or body cavities.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Sufentanil

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens
Addex Natriumklorid
Aminoplasmal E

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Assistance Publique Hopitaux De Paris
SERVICE DE PEDIATRIE GENERALE ET URGENCES PEDIATRIQUES - HUPSSD site Jean-Verdier APHP
Bondy, France
Assistance Publique Hopitaux De Paris
Service Pédiatrie - Reference centres for SCD -Hôpital Ambroise Paré
Boulogne-Billancourt, France
Assistance Publique Hopitaux De Paris
Paediatric emergency department
Boulogne-Billancourt, France
Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.