Simvastatin for Primary Sclerosing Cholangitis (PSC)

We are studying whether simvastatin can help people with PSC live longer without serious complications like bile duct cancer or the need for a transplant. We will also examine its effects on disease markers and symptoms.

>2 yearsEfficacy phase (II)Standard MedicinesOralHepatologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Simvastatin Sandoz
Simvastatin Sandoz is a medicine used to lower cholesterol and reduce the risk of heart disease and stroke.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Simvastatin
Simvastatin is a substance that lowers high cholesterol to help reduce the risk of heart attack and stroke.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alcosin
Alpheus
Antichol

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Danderyds Sjukhus AB
Department of Gastroenterology
Bergshamra, Sweden
Region Skane Skanes Universitetssjukhus
Department of Gastroenterology
Dalby, Sweden
Sahlgrenska University Hospital-Vastra Gotalandsregionen
Department of Gastroenterology
Göteborg, Sweden
Sponsor: Karolinska University Hospital
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.